Open School's progressive programs are rooted in  the tenets of open and constructivist education and self-directed learning. The district's only K-12 school, Open's academic program is designed for self-motivated and independent learners who want a family-like environment.

Johnson High School proudly showcases its eight new academies: Freshman Focus; Architecture, Construction and Engineering; Arts, Communications and Humanities; Business, Marketing and Management; Education and Human Services;  Health Sciences; Hospitality, Tourism and Recreation; and Natural Resources and Sciences.

Humboldt Senior High School offers a comprehensive curriculum with "rigor, relevance, and relationships" for all students. In the 9th Grade Academy, all students take core courses in English, math, social students and science in scheduled groups. Advisory focuses on helping students develop the tools to have a plan for life after high school, including a "Six-Year Plan" that is required for all students.

Harding High School is a comprehensive high school offering an educational program tailored to individual student needs and interests while promoting community and social awareness. Harding has five Small Learning Communities: Ninth Grade Academy; Academy of Fine Arts; Human Services Academy; Medical and Environmental Studies Academy; and Science, Engineering and Industrial Technology Academy.

As Minnesota’s oldest high school, Central High School has a long and impressive tradition of academic excellence. A national Blue Ribbon School of Excellence, Central has proven its success as a model for public education serving diverse students. The school’s rigorous academic program is based on state and national standards.

Arlington Senior High School is recognized as St. Paul's premiere "high tech" high school and offers the rigorous BioSMART program, which emphasizes Science, Math, Academic Rigor and Technology. The BioSMART program introduces Arlington students to career pathways in Bio Medical and Health Sciences; Bio Engineering and Technology; and Bio Business and Marketing.