Johnson High School proudly showcases its eight new academies: Freshman Focus; Architecture, Construction and Engineering; Arts, Communications and Humanities; Business, Marketing and Management; Education and Human Services;  Health Sciences; Hospitality, Tourism and Recreation; and Natural Resources and Sciences.

Humboldt Senior High School offers a comprehensive curriculum with "rigor, relevance, and relationships" for all students. In the 9th Grade Academy, all students take core courses in English, math, social students and science in scheduled groups. Advisory focuses on helping students develop the tools to have a plan for life after high school, including a "Six-Year Plan" that is required for all students.

Highland Park Senior High’s International Baccalaureate (IB) program is a comprehensive and rigorous two-year academic program for highly motivated students interested in a pre-university program. IB courses are offered across the curriculum and students choose how to participate in the program.

Harding High School is a comprehensive high school offering an educational program tailored to individual student needs and interests while promoting community and social awareness. Harding has five Small Learning Communities: Ninth Grade Academy; Academy of Fine Arts; Human Services Academy; Medical and Environmental Studies Academy; and Science, Engineering and Industrial Technology Academy.

Como Park is a vibrant and diverse, urban high school with many opportunities for all students to achieve, succeed and thrive.  We offer a solid academic framework from our excellent Special Education and English Language Learner programs to an Advanced Placement program that is one of the most successful in the state. We serve students of all abilities and interests.

As Minnesota’s oldest high school, Central High School has a long and impressive tradition of academic excellence. A national Blue Ribbon School of Excellence, Central has proven its success as a model for public education serving diverse students. The school’s rigorous academic program is based on state and national standards.

Arlington Senior High School is recognized as St. Paul's premiere "high tech" high school and offers the rigorous BioSMART program, which emphasizes Science, Math, Academic Rigor and Technology. The BioSMART program introduces Arlington students to career pathways in Bio Medical and Health Sciences; Bio Engineering and Technology; and Bio Business and Marketing.